Tobias, Joshua Wang, Veronique Giroux, Kathryn E. shown an explicit proliferation-differentiation gradient. Notch inhibition gathered undifferentiated basal keratinocytes with deregulated squamous cell differentiation in organoids. EoE patient-derived 3D organoids shown normal epithelial framework ex?in the lack of the EoE inflammatory milieu vivo. Arousal of esophageal 3D organoids with EoE-relevant cytokines led to a phenocopy of … Continue reading Tobias, Joshua Wang, Veronique Giroux, Kathryn E